
Description
Description
Dermorphin Peptide: Powerful Advancement in Research Analgesics
Dermorphin is an innovative hepta-peptide, first isolated from the skin of South American frogs of the genus Phyllomedusa. Renowned for its potent analgesic properties, Dermorphin stands out due to its ability to bind highly selectively and strongly to mu opioid receptors. Remarkably, Dermorphin is 30–40 times more potent than morphine, with a unique structure that features the rare D-amino acid, D-alanine. This peptide, while not found in mammals, is synthesized naturally in amphibians through a specialized post-translational modification.
Dermorphin's mechanism offers strong, long-lasting pain relief with less risk of tolerance and dependence compared to conventional opioids. Historically studied for postoperative and palliative use, Dermorphin has demonstrated unprecedented power in both animal and human models. Its use has been studied via both intravenous and intrathecal administration, showing rapid onset and extended duration of effect.
Potential Benefits of Dermorphin:
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Provides powerful, long-lasting pain relief
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Exhibits high selectivity for mu opioid receptors
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Demonstrates rapid onset of analgesia
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Far more potent than morphine
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May induce less tolerance and dependence versus traditional opioids
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Shows favorable safety profile in initial studies
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Has the potential to improve endocrine balance
Ailments and Conditions Dermorphin May Address:
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Acute and chronic pain
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Postoperative pain
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Cancer-related and palliative pain
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Pain refractory to conventional opioids
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Nociceptive pain conditions
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Intractable chronic pain
Advance research in pain control and opioid science—explore top-grade Dermorphin with Peptide Nova today.
*10MG Lyophilized Powder
THIS PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY.
*This product is intended for research use only. All Information on this website is for educational purposes only.
This product is not a food, drug, or supplement and may not be misbranded, misused or mislabeled as a food, drug, or supplement.
Details
Details
Who Can Benefit From Dermorphin?
Dermorphin is ideal for research teams devoted to exploring alternatives to traditional opioid analgesics. It is especially valuable for those investigating novel pain management therapies, opioid receptor pharmacology, or peptide-based drug development. Labs focused on neuroscience, postoperative care, or palliative approaches will find Dermorphin’s distinct properties to be a game-changing asset.
Research
Research
Links to Studies:
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6260176/
- https://pubmed.ncbi.nlm.nih.gov/7195758/
- https://www.sciencedirect.com/topics/neuroscience/dermorphin
- https://www.sciencedirect.com/science/article/abs/pii/0304394084903689
- https://www.pnas.org/doi/10.1073/pnas.89.15.7203
- https://pubmed.ncbi.nlm.nih.gov/6527833/
- https://www.sciencedirect.com/science/article/pii/0196978185903705
- https://academic.oup.com/painmedicine/article/20/10/2077/5464922
- https://en.wikipedia.org/wiki/Dermorphin
- https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.1981.tb16797.x
- https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/dta.1585
- https://www.abbiotec.com/peptides/dermorphin-peptide
- https://pubs.acs.org/doi/10.1021/jm00392a002
- https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/dermorphin
- https://www.peptide.com/product/dermorphin-77614-16-5/
- https://www.chromatographytoday.com/article/bioanalytical/40/unassigned-independent-article/bioanalysis-of-dermorphin-an-opioid-peptide-in-equine-urine-benefit-of-the-vip-heated-esi-technology-for-the-quantitative-analysis-of-thermally-labile-molecules/1335/download
Mechanism of Action
Mechanism of Action
Peptide Nova
DERMORPHIN 10MG
DERMORPHIN 10MG

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For research purposes only. Not for consumption, clinical use, or diagnostic purposes. Buyer assumes all responsibility for proper handling and use in compliance with applicable regulations.

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